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Importantly, even after the first fracture has occurred, there are effective treatments to decrease the risk of further fractures.

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• This information combined with clinical judgment and patient preference should lead to more appropriate testing and treatment of those at risk of fractures attributable to osteoporosis.
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Prevention, detection and treatment of osteoporosis should be a mandate of primary care providers. This Guide offers concise recommendations regarding prevention, risk assessment, diagnosis and treatment of osteoporosis in postmenopausal women and men age 50 and older. It includes indications for bone densitometry and fracture risk thresholds for intervention with pharmacologic agents.

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Although the majority of vertebral fractures are initially clinically silent, these fractures are often associated with symptoms of 5 pain, disability, deformity and mortality. Postural changes associated with kyphosis may limit activity, including bending and reaching. Multiple thoracic fractures may result in restrictive lung disease and lumbar fractures may alter abdominal anatomy, leading to constipation, abdominal pain, distention, reduced appetite and premature satiety. Vertebral fractures, whether clinically apparent or silent, are major predictors of future fracture risk, up to 5-fold for subsequent vertebral fracture and 2- to 3-fold for fractures at other sites. Wrist fractures are less disabling but can interfere with some activities of daily living as much as hip or vertebral fractures. Fractures can also cause psychosocial symptoms, most notably depression and loss of self- esteem, as patients grapple with pain, physical limitations, and lifestyle and cosmetic changes.

Economic Toll Annually, two million fractures are attributed to osteoporosis, causing more than 432,000 hospital admissions, almost 2.

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Medicare where To Order Trinidazole Online pays for approximately 80 percent of these fractures, with hip fractures accounting for 72 percent of fracture costs. Peak bone where To Order Trinidazole Online is determined largely by genetic factors, with contributions from 8 nutrition, endocrine status, physical activity and health during growth. The process of bone remodeling that maintains a healthy skeleton may be considered a preventive maintenance program, continually removing older bone and replacing it with new bone. Bone loss occurs when this balance is altered, resulting in greater bone removal than replacement.

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